Corin Wagen

My personal blog: chemistry, theology, metascience, and whatever else I'm thinking about.

Launched 3 years ago

Tool Use and "AI Scientists"

As AI systems get more powerful and better at scientific tasks, what will the new research ecosystem look like?

Jun 18

Multiparameter Compound Optimization with LLMs

Yesterday, an interesting paper was released by Prescient Design (Genentech), “Evaluating the Progression of Large Language Model Capabilities for…

Apr 21

Book Review: The Reformation As Renewal

TW: stridently anti–Roman Catholic rhetoric, medieval realist metaphysics

Feb 17

Horizontalization in Biotech

Long ago, there were no software companies.

Jan 13

Books from 2025

(Previously: 2022, 2023, 2024.)

Dec 23, 2025

Seven Thoughts on "AI Scientists"

Last week I had the privilege of attending the 2025 Progress Conference, which brought together a diverse cadre of people working on progress…

Oct 21, 2025

Vibe-Coding a Coloring-Page Generator

I don’t write about my non-working life much on the Internet; my online presence has been pretty closely tied to Rowan and I try to adhere to some level…

Sep 6, 2025

Long-Range Forces and Neural Network Potentials

I’ve been sitting on this post for well over a year.

Aug 16, 2025